1. Catalog
  2. Nodes
  3. a(MESH:"Pathogen-Associated Molecular Pattern Molecules")

a(MESH:"Pathogen-Associated Molecular Pattern Molecules")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Pathogen-Associated Molecular Pattern Molecules
Namespace
mesh
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/mesh-names.belns

Appears in Networks 1

The role of inflammasome in Alzheimer’s disease v1.0.3

In-Edges 0

Out-Edges 2

a(MESH:"Pathogen-Associated Molecular Pattern Molecules") increases complex(GO:"inflammasome complex") View Subject | View Object

In response to danger signals, inflammasomes assemble by self-oligomerizing the NLRs through interactions with the NACHT domain (van de Veerdonk et al., 2011) PubMed:24561250

Appears in Networks:
Annotations
Confidence
High

a(MESH:"Pathogen-Associated Molecular Pattern Molecules") increases act(complex(GO:"inflammasome complex")) View Subject | View Object

The activators of the inflammasomes can be divided into two categories; pathogen associated molecular patterns (PAMPs) activate a host-defense reaction, and damage associated molecular patterns (DAMPs) activate a self-defense mechanism in response to danger signals (Salminen et al., 2008) PubMed:24561250

Appears in Networks:
Annotations
Confidence
High

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.