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Appears in Networks 2

albuquerque2009 v1.0.0

This file encodes the article Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function by Albuquerque et al, 2009

In-Edges 2

path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:Tremor) View Subject | View Object

Parkinson’s disease (PD) is characterized by selective damage to dopaminergic nigrostriatal neurons and is clinically revealed by motor deficits, including rigidity, tremor, and bradykinesia. Dopamine replacement therapy (usually with L-dopa) is the most common treatment, although this drug loses efficacy over time. PubMed:19126755

Appears in Networks:
Annotations
MeSH
Dopaminergic Neurons
Text Location
Review

a(CHEBI:Mecamylamine) increases path(MESH:Tremor) View Subject | View Object

In addition, mecamylamine can produce CNS effects that include tremor, mental confusion, seizures, mania, and depression but the mechanisms by which these effects are produced are unclear PubMed:28391535

Out-Edges 1

path(MESH:Tremor) positiveCorrelation path(MESH:"Parkinson Disease") View Subject | View Object

Parkinson’s disease (PD) is characterized by selective damage to dopaminergic nigrostriatal neurons and is clinically revealed by motor deficits, including rigidity, tremor, and bradykinesia. Dopamine replacement therapy (usually with L-dopa) is the most common treatment, although this drug loses efficacy over time. PubMed:19126755

Appears in Networks:
Annotations
MeSH
Dopaminergic Neurons
Text Location
Review

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.