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bp(GO:"cellular response to DNA damage stimulus")

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Entity

Name
cellular response to DNA damage stimulus
Namespace
go
Namespace Version
20190207
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/a5b84013a08880975ca84f40999e4404b14a97e2/external/go-names.belns

Appears in Networks 2

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways v1.0.0

Activation and regulation of the inflammasomes v1.0.0

In-Edges 1

p(HGNC:FKBP5) regulates bp(GO:"cellular response to DNA damage stimulus") View Subject | View Object

Corroborating our results, a recent systematic small interfering RNA (siRNA) screen identified FKBP51 as a factor in modulating the cellular response to DNA damage (Cotta-Ramusino et al., 2011) PubMed:25036637

Appears in Networks:

Out-Edges 1

bp(GO:"cellular response to DNA damage stimulus") increases complex(GO:ripoptosome) View Subject | View Object

Furthermore, in response to genotoxic stress, the ripoptosome assembles and activates caspase 8. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High
NeuroMMSigDB
Caspase subgraph

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.