RM-532-46

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Entity

Name: RM-532-46
Namespace: HBP
Namespace Version: 20190307
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/209a3048003c8d92394e6b64778447bd996a21e6/export/hbp-names.belns

Out-Edges 1

a(HBP:"RM-532-46") decreases act(p(HGNC:HSD17B10)) View Subject | View Object

Interestingly, during the search for inhibitors of 17β-HSD isoforms for the treatment of estrogen- related diseases, 127 Ayan et.al identified the steroidal compound RM-532-46 (8) as a reversible ABAD inhibitor (IC 50 = 0.55 M). PubMed:30444369

Appears in Networks:

Amyloid-Binding Alcohol Dehydrogenase (ABAD) Inhibitors for the Treatment of Alzheimer’s Disease v1.0.0

Annotations

MeSH: Neurons

About

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

`a(HBP:"RM-532-46")`