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bp(GO:"JNK cascade")

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Entity

Name
JNK cascade
Namespace
go
Namespace Version
20190224
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/go-names.belns

Appears in Networks 1

Nuclear Factor Kappa-light-chain-enhancer of Activated B Cells (NF-κB) - a Friend, a Foe, or a Bystander - in the Neurodegenerative Cascade and Pathogenesis of Alzheimer's Disease v1.0.0

In-Edges 1

a(CHEBI:"amyloid-beta") increases bp(GO:"JNK cascade") View Subject | View Object

Amyloid-β has also been demonstrated to induce apoptosis via the JNK1/c-Jun/Fas ligand signaling cascade [110], which results in NF-κB activation PubMed:28745240

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

Out-Edges 2

bp(GO:"JNK cascade") increases bp(GO:"apoptotic process") View Subject | View Object

Amyloid-β has also been demonstrated to induce apoptosis via the JNK1/c-Jun/Fas ligand signaling cascade [110], which results in NF-κB activation PubMed:28745240

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

bp(GO:"JNK cascade") increases act(complex(GO:"NF-kappaB complex")) View Subject | View Object

Amyloid-β has also been demonstrated to induce apoptosis via the JNK1/c-Jun/Fas ligand signaling cascade [110], which results in NF-κB activation PubMed:28745240

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.