1. Catalog
  2. Nodes
  3. p(HGNC:PPP2R5A, pmod(Ph, Ser))

p(HGNC:PPP2R5A, pmod(Ph, Ser))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
PPP2R5A
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Protein phosphatase 2A dysfunction in Alzheimer’s disease v1.0.0

In-Edges 2

p(FPLX:PKA) increases p(HGNC:PPP2R5A, pmod(Ph, Ser)) View Subject | View Object

Adding another layer of complexity to the regulation of PP2A holoenzymes, protein kinase A-mediated serine phosphorylation of selective PPP2R5A and PPP2R5D regulatory subunits belonging to the B’family can also modulate PP2A catalytic activity (Ahn et al.,2007; Kirchhefer et al.,2014). PubMed:24653673

Appears in Networks:

p(HGNC:PPP2R5A) hasVariant p(HGNC:PPP2R5A, pmod(Ph, Ser)) View Subject | View Object

Appears in Networks:

Out-Edges 1

p(HGNC:PPP2R5A, pmod(Ph, Ser)) regulates act(complex(GO:"protein phosphatase type 2A complex")) View Subject | View Object

Adding another layer of complexity to the regulation of PP2A holoenzymes, protein kinase A-mediated serine phosphorylation of selective PPP2R5A and PPP2R5D regulatory subunits belonging to the B’family can also modulate PP2A catalytic activity (Ahn et al.,2007; Kirchhefer et al.,2014). PubMed:24653673

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.