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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

path(MESH:"Vascular System Injuries") positiveCorrelation rxn(reactants(a(CHEBI:superoxide), p(HGNC:HBB)), products(a(CHEBI:"hydrogen peroxide"))) View Subject | View Object

Furthermore superoxide can react with Hb to produce hydrogen peroxide (H2O2), a well defined prooxidative molecule that causes vascular injury (1). PubMed:19276082

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Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Aorta
Text Location
Discussion

Out-Edges 4

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.