Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Appears in Networks 1

In-Edges 0

Out-Edges 2

a(HBP:AG18051) decreases act(p(HGNC:HSD17B10)) View Subject | View Object

A potent ABAD inhibitor, AG18051 (1), containing a pyrazolo[3,4-d] pyrimidine-4(1H)-thione backbone (IC 50 = 92 nM) has been reported. PubMed:30444369

a(HBP:AG18051) decreases act(a(HBP:"amyloid-beta aggregates")) View Subject | View Object

Moreover, it has been shown to ameliorate Aβ-induced toxicity at the cellular level. 7 PubMed:30444369


BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.