APP695

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name: APP695
Namespace: HBP
Namespace Version: 20190416
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/b689162f627a65a2a04f09fc62c80d7971198147/export/hbp-names.belns

In-Edges 1

a(CHEBI:nicorandil) decreases p(HBP:APP695) View Subject | View Object

Nicorandil, ATP-sensitive potassium channel opener, reduced apo- ptosis and decreased oxidative stress, downregulated APP695 mRNA and APP695 protein expression, also reduced Aβ 42 levels in the medium [90]. PubMed:27288790

Appears in Networks:

Upstream regulators and downstream effectors of NF-κBinAlzheimer's disease v1.0.0

Annotations

MeSH: Cerebral Cortex
MeSH: Hippocampus

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

`p(HBP:APP695)`