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p(HGNC:TFAP2B)

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Entity

Name
TFAP2B
Namespace
hgnc
Namespace Version
20190224
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/hgnc-names.belns

Appears in Networks 1

Activity-dependent neuroprotective protein (ADNP) is an alcohol-responsive gene and negative regulator of alcohol consumption in female mice v1.0.0

In-Edges 3

p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) increases p(HGNC:TFAP2B) View Subject | View Object

For example, one of these common genes was transcription factor AP2 beta (TFAP2b), which is downregulated by chronic alcohol exposure [41]. This gene had a 3.8-fold increased expression in female Adnp+/− mice, and in contrast, a five-fold decreased expression in male Adnp+/− mice, as compared to sex-matched Adnp+/+controls. PubMed:30008470

Appears in Networks:
Annotations
Gender
Female

p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) decreases p(HGNC:TFAP2B) View Subject | View Object

For example, one of these common genes was transcription factor AP2 beta (TFAP2b), which is downregulated by chronic alcohol exposure [41]. This gene had a 3.8-fold increased expression in female Adnp+/− mice, and in contrast, a five-fold decreased expression in male Adnp+/− mice, as compared to sex-matched Adnp+/+controls. PubMed:30008470

Appears in Networks:
Annotations
Gender
Male

path(MESH:"Alcohol Drinking") decreases p(HGNC:TFAP2B) View Subject | View Object

For example, one of these common genes was transcription factor AP2 beta (TFAP2b), which is downregulated by chronic alcohol exposure [41]. This gene had a 3.8-fold increased expression in female Adnp+/− mice, and in contrast, a five-fold decreased expression in male Adnp+/− mice, as compared to sex-matched Adnp+/+controls. PubMed:30008470

Appears in Networks:

Out-Edges 0

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.