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p(HBP:"tubulin-binding repeat 4")

Equivalencies: 1 | Classes: 0 | Children: 1 | Explore

Entity

Name
tubulin-binding repeat 4
Namespace
HBP
Namespace Version
20181119
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/90e1cb9e5e882703380c9db8d4915ac6f3cba137/export/hbp-names.belns

Appears in Networks 3

Tau Biochemistry v1.2.5

Tau Biochemistry Section of NESTOR

TAU and Interaction Partners v1.2.5

TAU Interactions Section of NESTOR

Tau Modifications v1.9.5

Tau Modifications Sections of NESTOR

In-Edges 3

p(HBP:"Tau isoform F (441 aa)", frag("337_367")) equivalentTo p(HBP:"tubulin-binding repeat 4") View Subject | View Object

Appears in Networks:

p(HBP:"VQIVYK motif") isA p(HBP:"tubulin-binding repeat 4") View Subject | View Object

Appears in Networks:

p(HGNC:MAPT, pmod(Ph, Ser, 352)) partOf p(HBP:"tubulin-binding repeat 4") View Subject | View Object

Appears in Networks:

Out-Edges 4

p(HBP:"tubulin-binding repeat 4") partOf a(HBP:"microtubule-binding region") View Subject | View Object

Appears in Networks:

p(HBP:"tubulin-binding repeat 4") equivalentTo p(HBP:"Tau isoform F (441 aa)", frag("337_367")) View Subject | View Object

Appears in Networks:

p(HBP:"tubulin-binding repeat 4") directlyIncreases complex(p(HGNC:MAPT), p(HGNCGENEFAMILY:Tubulins)) View Subject | View Object

Tau binds to microtubule through the C-terminal repeat domain and 4R bind more tightly than 3R, while phosphorylation, especially of the repeat domain tends to decrease binding. PubMed:17493042

Appears in Networks:
Annotations
Uberon
brain

p(HBP:"tubulin-binding repeat 4") partOf p(HBP:"4R tau") View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.