1. Catalog
  2. Nodes
  3. p(HGNC:CDC34, var("?"))

p(HGNC:CDC34, var("?"))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
CDC34
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

The Ubiquitin Proteasome System in Neurodegenerative Diseases: Sometimes the Chicken, Sometimes the Egg v1.0.0

In-Edges 1

p(HGNC:CDC34) hasVariant p(HGNC:CDC34, var("?")) View Subject | View Object

Appears in Networks:

Out-Edges 2

p(HGNC:CDC34, var("?")) decreases a(MESH:"Inclusion Bodies") View Subject | View Object

Tentative support for this idea was obtained in a cell model of HD, where expression of a dominant-negative variant of the E2 Cdc34p decreased the formation of intranuclear inclusions but increased the likelihood of cell death (Saudou et al., 1998). PubMed:14556719

Appears in Networks:
Annotations
MeSH
Huntington Disease

p(HGNC:CDC34, var("?")) increases bp(GO:"cell death") View Subject | View Object

Tentative support for this idea was obtained in a cell model of HD, where expression of a dominant-negative variant of the E2 Cdc34p decreased the formation of intranuclear inclusions but increased the likelihood of cell death (Saudou et al., 1998). PubMed:14556719

Appears in Networks:
Annotations
MeSH
Huntington Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.