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path(MESH:"Motor Activity")

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Entity

Name
Motor Activity
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/mesh-names.belns

Appears in Networks 2

Discriminative Stimulus Properties of S(−)-Nicotine: “A Drug for All Seasons v1.0.0

Activity-dependent neuroprotective protein deficiency models synaptic and developmental phenotypes of autism-like syndrome v1.0.0

In-Edges 4

a(CHEBI:nicotine) negativeCorrelation path(MESH:"Motor Activity") View Subject | View Object

For example, in rodents, administration of low doses of nicotine produced increased motor activity whereas high doses produced decreased motor activity (e.g.,[17, 18]) PubMed:28391535

Appears in Networks:

a(PUBCHEM:9832404) increases path(MESH:"Motor Activity") View Subject | View Object

We then measured the latency to fall off an inverted cage lid (hanging wire) and found a highly significant impairment (decreased latency) in male Adnp+/– mice and a complete reversal with NAP treatment (Figure 7A). The females were not affected in this behavior, indicating sex differences in motor behavior and development in the haploinsufficient mice PubMed:30106381

Appears in Networks:
Annotations
Gender
Male

p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) decreases path(MESH:"Motor Activity") View Subject | View Object

We then measured the latency to fall off an inverted cage lid (hanging wire) and found a highly significant impairment (decreased latency) in male Adnp+/– mice and a complete reversal with NAP treatment (Figure 7A). The females were not affected in this behavior, indicating sex differences in motor behavior and development in the haploinsufficient mice PubMed:30106381

Appears in Networks:
Annotations
Gender
Male

p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) causesNoChange path(MESH:"Motor Activity") View Subject | View Object

We then measured the latency to fall off an inverted cage lid (hanging wire) and found a highly significant impairment (decreased latency) in male Adnp+/– mice and a complete reversal with NAP treatment (Figure 7A). The females were not affected in this behavior, indicating sex differences in motor behavior and development in the haploinsufficient mice PubMed:30106381

Appears in Networks:
Annotations
Gender
Female

Out-Edges 1

path(MESH:"Motor Activity") negativeCorrelation a(CHEBI:nicotine) View Subject | View Object

For example, in rodents, administration of low doses of nicotine produced increased motor activity whereas high doses produced decreased motor activity (e.g.,[17, 18]) PubMed:28391535

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.