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GABAergic neuron

Name
GABAergic neuron
Namespace Keyword
Cell
Namespace
Cell Ontology (CL)
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/cell/cell-20170511.belanno

Sample Annotated Edges 5

a(CHEBI:"amyloid-beta polypeptide 42") decreases bp(MESH:"Synaptic Potentials") View Subject | View Object

They demonstrated that Abeta1-42 drives a reversible inhibition of nAChR-mediated currents in hippocampal GABAergic neurons recorded from rat slices. In these experimental conditions the most effective Abeta1-42 concentration was 500 nM, but inhibition was found also at the lower concentration of 100 nM PubMed:25514383

Appears in Networks:
Annotations
Cell Ontology (CL)
GABAergic neuron
MeSH
Hippocampus

a(CHEBI:"amyloid-beta polypeptide 42") decreases act(p(FPLX:CHRN)) View Subject | View Object

They demonstrated that Abeta1-42 drives a reversible inhibition of nAChR-mediated currents in hippocampal GABAergic neurons recorded from rat slices. In these experimental conditions the most effective Abeta1-42 concentration was 500 nM, but inhibition was found also at the lower concentration of 100 nM PubMed:25514383

Appears in Networks:
Annotations
Cell Ontology (CL)
GABAergic neuron
MeSH
Hippocampus

act(p(FPLX:CHRN)) increases bp(MESH:"Synaptic Potentials") View Subject | View Object

They demonstrated that Abeta1-42 drives a reversible inhibition of nAChR-mediated currents in hippocampal GABAergic neurons recorded from rat slices. In these experimental conditions the most effective Abeta1-42 concentration was 500 nM, but inhibition was found also at the lower concentration of 100 nM PubMed:25514383

Appears in Networks:
Annotations
Cell Ontology (CL)
GABAergic neuron
MeSH
Hippocampus

p(HGNC:MAPT, var("p.Lys280del")) decreases bp(GO:"dorsal spinal cord development") View Subject | View Object

In contrast, we observed severe developmental defects in the pro-aggregant strain (BR5707) that manifest as increased numbers of persist- ent gaps in both the ventral and dorsal neural cords (mean + SD ¼ 2.7 + 1.4 gaps at the L3 stage). PubMed:22611162

Appears in Networks:
Annotations
Cell Ontology (CL)
GABAergic neuron

p(HGNC:MAPT, var("p.Lys280del")) decreases bp(GO:"ventral spinal cord development") View Subject | View Object

In contrast, we observed severe developmental defects in the pro-aggregant strain (BR5707) that manifest as increased numbers of persist- ent gaps in both the ventral and dorsal neural cords (mean + SD ¼ 2.7 + 1.4 gaps at the L3 stage). PubMed:22611162

Appears in Networks:
Annotations
Cell Ontology (CL)
GABAergic neuron

Showing 5 of 5 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.