p(HGNC:HBB) increases bp(HM:"macrophage M1 polarization")

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PubMed:26675351

This is the case in a mouse model of SCD, which is hallmarked by hemolysis, increased circulating Hb/heme, and low levels of Hp and Hx and shows elevated hepatic macrophage iron levels and M1 polarization.

Related Edges 1

• a(CHEBI:heme) increases bp(HM:"macrophage M1 polarization")

Cell Ontology (CL)

macrophage

MeSH

Liver

MeSH

Anemia, Sickle Cell

Text Location

Discussion

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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