a(CHEBI:peroxynitrite) increases p(MESH:Proteins, pmod(HBP:nitration))

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PubMed:28745240

NF-κB activation also protects hippocampal neurons from oxidative stress-induced apoptosis by inducing manganese superoxide dismutase (MnSOD) expression and mitigating peroxynitrite-induced protein nitration

Related Edges 4

• bp(MESH:"Oxidative Stress") increases bp(GO:"apoptotic process")
• act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"neuron death")
• act(complex(GO:"NF-kappaB complex")) increases p(HGNC:SOD2)
• act(complex(GO:"NF-kappaB complex")) decreases p(MESH:Proteins, pmod(HBP:nitration))

MeSH

Hippocampus

MeSH

Alzheimer Disease

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