bp(MESH:"Oxidative Stress") increases bp(GO:"apoptotic process")

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PubMed:28745240

NF-κB activation also protects hippocampal neurons from oxidative stress-induced apoptosis by inducing manganese superoxide dismutase (MnSOD) expression and mitigating peroxynitrite-induced protein nitration

Related Edges 4

• a(CHEBI:peroxynitrite) increases p(MESH:Proteins, pmod(HBP:nitration))
• act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"neuron death")
• act(complex(GO:"NF-kappaB complex")) increases p(HGNC:SOD2)
• act(complex(GO:"NF-kappaB complex")) decreases p(MESH:Proteins, pmod(HBP:nitration))

MeSH

Hippocampus

MeSH

Alzheimer Disease

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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