a(CHEBI:heme) increases p(MGI:Vcam1)

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PubMed:24904418

Heme activates endothelial cells inducing the expression of the adhesion molecules ICAM-1 (intercellular adhesion molecule 1), VCAM-1 (vascular cell adhesion molecule 1), E-selectin, Pselectin, and von Willebrand factor (VWF; Wagener et al., 1997; Belcher et al., 2014) and causes neutrophil migration (GraçaSouza et al., 2002; Porto et al., 2007).

Related Edges 6

• a(CHEBI:heme) increases p(MGI:Icam1)
• a(CHEBI:heme) increases bp(GO:"endothelial cell activation")
• a(CHEBI:heme) increases p(HGNC:SELE)
• a(CHEBI:heme) increases p(HGNC:SELP)
• a(CHEBI:heme) increases p(MGI:Vwf)
• a(CHEBI:heme) increases bp(GO:"neutrophil migration")

Cell Ontology (CL)

erythrocyte

Text Location

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