complex(p(HGNC:MAPT), p(HGNC:MAPT), p(HGNC:MAPT)) increases a(HBP:"Tau aggregates")

PubMed:25887395

Next we analyzed fractions for seeding activity in the P301S- Nluc/Cluc HEK293 cell lines by a split-luciferase complemen- tation assay, comparing AD and control brains. Trimers and larger BD Tau assemblies induced intracellular aggregation, but not monomer or dimer.

MeSH

Brain

MeSH

Alzheimer Disease

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