p(HBP:"3R tau") negativeCorrelation bp(GO:"neurofibrillary tangle assembly")

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PubMed:26655600

However, granule cells of the dentate gyrus mainly express 3R isoforms, which resist Tau aggregation in AD, but accumulate 3R aggregates in Pick's disease [14]. 3R Tau is a major Tau isoform in laser microdissected Pick bodies [15].

Related Edges 3

• bp(GO:"neurofibrillary tangle assembly") negativeCorrelation p(HBP:"3R tau")
• complex(GO:"Pick body") positiveCorrelation p(HBP:"3R tau")
• p(HBP:"3R tau") positiveCorrelation complex(GO:"Pick body")

Uberon

dentate gyrus granule cell layer

Disease Ontology (DO)

Alzheimer's disease

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