a(PUBCHEM:4162) decreases act(p(FPLX:PPP2))

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PubMed:23454242

Potent tumor promoter, Okadaic acid (a microbial toxin), inhibits the enzymatic activity of PP2Ac and thereby has facilitated various studies to understand the functional aspects of PP2A and other phosphatases [12]. Other than Okadaic acid, calyculin A, microcystin, cantharidin, nodularm, fostriecin and tautomycin are able to inhibit PP2A activity at different IC50 values [48].

Related Edges 7

• a(CHEBI:"okadaic acid") increases path(MESH:Neoplasms)
• a(CHEBI:"okadaic acid") decreases act(p(FPLX:PPP2C))
• a(CHEBI:Tautomycin) decreases act(p(FPLX:PPP2))
• a(CHEBI:cantharidin) decreases act(p(FPLX:PPP2))
• a(CHEBI:microcystin) decreases act(p(FPLX:PPP2))
• a(PUBCHEM:5311365) decreases act(p(FPLX:PPP2))
• a(PUBCHEM:6913994) decreases act(p(FPLX:PPP2))

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