a(CHEBI:"glutamate(2-)") directlyIncreases act(p(MESH:D017470))

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PubMed:16273023

First, the presence of elevated neurotransmitter levels in the synapse under resting conditions can be thought of as a constant 'background signal,' leading to chronic low-level activation of glutamatergic receptors on postsynaptic neurons and possibly neuronal death.

Related Edges 2

• bp(GO:"GO:0070997") association act(p(MESH:D017470))
• act(p(MESH:D017470)) association bp(GO:"GO:0070997")

MeSH

Post-Synaptic Density

Cell Ontology (CL)

glial cell

Disease Ontology (DO)

Alzheimer's disease

MeSH

Frontal Lobe

MeSH

Temporal Lobe

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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