path(MESH:D000544) increases act(p(HGNC:MMP9))

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PubMed:18986241

We found an upregulation of MMP-9 protein levels and activity in both AD and MCI brains, which correlated inversely with cognitive status (Figure 1B) [75]. Since tissue alterations are often reflected in bodily fluids, determination of MMPs in blood, urine and CSF has been recommended as potential biomarkers to act as diagnostic measures to characterize the disease process that occurs in the brain [76–78]. Interestingly, plasma MMP-9 was increased in MCI and AD [77].

Related Edges 3

• act(p(HGNC:MMP9)) positiveCorrelation path(MESH:D003072)
• path(MESH:D003072) positiveCorrelation act(p(HGNC:MMP9))
• path(MESH:D060825) increases act(p(HGNC:MMP9))

MeSH

Brain

MeSH

Plasma

MeSH

Cognitive Dysfunction

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