path(MESH:D003072) positiveCorrelation act(p(HGNC:MMP9))

View Subject View Object

PubMed:18986241

We found an upregulation of MMP-9 protein levels and activity in both AD and MCI brains, which correlated inversely with cognitive status (Figure 1B) [75]. Since tissue alterations are often reflected in bodily fluids, determination of MMPs in blood, urine and CSF has been recommended as potential biomarkers to act as diagnostic measures to characterize the disease process that occurs in the brain [76–78]. Interestingly, plasma MMP-9 was increased in MCI and AD [77].

Related Edges 3

• act(p(HGNC:MMP9)) positiveCorrelation path(MESH:D003072)
• path(MESH:D000544) increases act(p(HGNC:MMP9))
• path(MESH:D060825) increases act(p(HGNC:MMP9))

MeSH

Brain

MeSH

Plasma

MeSH

Cognitive Dysfunction

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---