p(HGNC:HBB) increases a(CHEBI:heme)

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PubMed:26974230

Exposure to Hb and its oxidized products increases heme overload on the AT1 cells. Heme overload induces the expression of HO-1 and iron-sequestering proteins, such as ferritin.

Related Edges 2

• a(CHEBI:heme) increases p(MGI:Hmox1)
• a(CHEBI:heme) increases p(MGI:Fth1)

Cell Ontology (CL)

endothelial cell

MeSH

Mitochondria

Text Location

Discussion

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