a(MESH:"xestospongin C") decreases act(p(HGNC:CHRNA7))

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PubMed:26088141

We confirmed the involvement of IP3Rs in choline-induced calcium transients at the GC of PC12 cells. Cells were preincubated with the IP3R blocker xestospongin C (1 μM) prior to imaging. As shown in Fig. 7, A–C, pretreatment with xestospongin C reduced the α7 nAChR calcium response peak by 46.82% in α7 cells (peak: 1308.43% ΔF/Fθ ± −238.13%; + xestospongin C = 695.80% ΔF/Fθ ± 101.46%).

Related Edges 1

• a(MESH:"xestospongin C") decreases bp(GO:"calcium-mediated signaling")

MeSH

PC12 Cells

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