p(FPLX:NFkappaB) association bp(GO:"neuron differentiation")

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PubMed:27288790

In the nervous system, NF-κB has been proposed to serve important function by acting as a transcription regulator: it has roles in inflammation, neuronal survival, differentiation, apoptosis, neurite outgrowth, and synaptic plasticity [5], which are impaired in the progression of various neurodegenerative diseases especially in AD.

Related Edges 13

• bp(GO:"apoptotic process") association p(FPLX:NFkappaB)
• bp(GO:"negative regulation of neuron apoptotic process") association p(FPLX:NFkappaB)
• bp(GO:"neuron differentiation") association p(FPLX:NFkappaB)
• bp(GO:"regulation of synaptic plasticity") association p(FPLX:NFkappaB)
• bp(GO:"regulation of synaptic plasticity") negativeCorrelation path(MESH:"Alzheimer Disease")
• bp(MESH:"Neuronal Outgrowth") association p(FPLX:NFkappaB)
• p(FPLX:NFkappaB) association path(MESH:Inflammation)
• p(FPLX:NFkappaB) association bp(GO:"negative regulation of neuron apoptotic process")
• p(FPLX:NFkappaB) association bp(GO:"apoptotic process")
• p(FPLX:NFkappaB) association bp(MESH:"Neuronal Outgrowth")
• p(FPLX:NFkappaB) association bp(GO:"regulation of synaptic plasticity")
• path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"regulation of synaptic plasticity")
• path(MESH:Inflammation) association p(FPLX:NFkappaB)

MeSH

Nervous System

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