p(MGI:Hpx) negativeCorrelation bp(GO:"inflammatory response")

View Subject View Object

PubMed:26675351

In conclusion, an Hx-based therapy shows beneficial effects, in that it counteracts heme-induced proinflammatory activation of macrophages and attenuates some of its pathophysiologic consequences, such as chronic inflammation, hepatic fibrosis, and apoptosis (Figure 7E).

Related Edges 7

• bp(GO:"inflammatory response") negativeCorrelation p(MGI:Hpx)
• bp(MESH:Apoptosis) negativeCorrelation p(MGI:Hpx)
• p(MGI:Hpx) negativeCorrelation path(MESH:Inflammation)
• p(MGI:Hpx) negativeCorrelation path(MESH:Fibrosis)
• p(MGI:Hpx) negativeCorrelation bp(MESH:Apoptosis)
• path(MESH:Fibrosis) negativeCorrelation p(MGI:Hpx)
• path(MESH:Inflammation) negativeCorrelation p(MGI:Hpx)

Cell Ontology (CL)

macrophage

MeSH

Liver

MeSH

Anemia, Sickle Cell

Text Location

Results

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---