a(MESH:Nicotine) decreases p(MESH:"Receptors, Nicotinic")

PubMed:28901280

Chronic nicotine exposure induces neural adaptations that change cell physi- ology and behaviour mainly as a result of activation and/or desensitisation of nAChRs. Studies of the brains of animals and smokers chronically exposed to nicotine have shown an increase in the number of nAChRs (up-regulation).

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