bp(GO:"action potential initiation") increases act(a(MESH:"Perforant Pathway"))

PubMed:19126755

It is noteworthy that, via such mechanisms, alpha7 nAChR activation could trigger rebound burst firing in SLM interneurons even in the absence of excitation (256). Burst firing in SLM interneurons suppresses spikes in pyramidal neurons evoked by stimulation of Schaffer collaterals (134), and, thereby allows selective activation of the pyramidal cells via the perforant pathway.

Related Edges 2

• bp(GO:"action potential initiation") decreases a(MESH:"Electric Stimulation", loc(GO:"Schaffer axon collateral"))
• act(p(HGNC:CHRNA7)) increases bp(GO:"action potential initiation")

Uberon

hippocampus stratum lacunosum moleculare

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