a(CHEBI:heme) increases p(HGNC:CD86)

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PubMed:26675351

Likewise, heme and FeNTA treatment causes the induction of the M1 markers MHCII, CD86, CD14, TNFα, IL-6, and IL1β and a decrease in the M2 markers CD206, IL-10, and Arginase-1 (the last with FeNTA only) in M0 BMDMs (Figure 3A; supplemental Figures 5, 6A, and 7).

Related Edges 7

• a(CHEBI:heme) increases p(HGNC:IL1B)
• a(CHEBI:heme) increases p(HGNC:IL6)
• a(CHEBI:heme) increases complex(SCOMP:"MHC Class II Complex")
• a(CHEBI:heme) increases p(HGNC:CD14)
• a(CHEBI:heme) decreases p(HGNC:MRC1)
• a(CHEBI:heme) decreases p(HGNC:IL10)
• a(CHEBI:heme) decreases p(HGNC:ARG1)

Cell Ontology (CL)

macrophage

MeSH

Liver

MeSH

Anemia, Sickle Cell

Text Location

Results

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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