path(MESH:D000544) decreases bp(GO:"GO:0014047")

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PubMed:16273023

In patients with Alzheimer's disease, available evidence points to a disruption in the glutamatergic neurotransmission cycle at the point of glial cell reuptake of free glutamate from the synapse. Neuropathologic studies have documented reduced levels of glutamate reuptake in the frontal and temporal cortices of patients with Alzheimer's disease,10 possibly due to oxidative modification of the glutamate transporter 1 molecule. Furthermore, diminished uptake by vesicular glutamate transporter has been reported in patients with Alzheimer's disease

Related Edges 1

• path(MESH:D000544) decreases bp(GO:"GO:0051935")

Cell Ontology (CL)

glial cell

Disease Ontology (DO)

Alzheimer's disease

MeSH

Frontal Lobe

MeSH

Temporal Lobe

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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