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In the hippocampal and cortical tissues of all AD cases examined, neuronal staining for ERα was a prominent finding, both with a weak cytoplasmic stain, but often specifically with a fibrillar appearance suggesting ERα was in neurofibrillary tangles (Fig. 1A), also shown at a higher magnification (Fig. 1B).

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.