act(p(FPLX:NFkappaB)) regulates a(MESH:Interleukins)

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PubMed:29179999

NF-B activation mediates the expression of the pro-oxidant NAPDH oxidase, cyclooxygenase 2 (COX2), interleukins and the antioxidant enzyme, superoxide dismutase (SOD) [78]. Additionally, NF-B activity is associated with the expression of BACE1 [79] and the activation of nucleotide-binding oligomerization domain-like receptor (NALP) 3 inflammosome [80].

Related Edges 4

• act(p(FPLX:NFkappaB)) regulates p(FPLX:"NADPH_oxidase")
• act(p(FPLX:NFkappaB)) regulates p(HGNC:PTGS2)
• act(p(FPLX:NFkappaB)) regulates p(FPLX:SOD)
• act(p(FPLX:NFkappaB)) increases p(HGNC:BACE1)

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