Citation

PubMed: 22002427

Title: Truncation of tau at E391 promotes early pathologic changes in transgenic mice.
Journal: Journal of neuropathology and experimental neurology
Volume: 70
Issue: None
Pages: 1006-19
Date: 2011-11-01
Authors: Kraemer BC | Leverenz JB | McMillan PJ | Raskind M | Robinson L | Schellenberg G

Evidence 47928e448d
JSON

E391-3610 mice (higher expressers) exhibit robust somatodendritic distribution of phospho- Ser 202/Thr 205 tau throughout the cortex, in hippocampal CA3 pyramidal neurons, CA1 apical dendrites and cell bodies and dentate granule cells.

a(GO:"neurofibrillary tangle") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 202)) View Subject | View Object

Appears in Networks:

Tau Modifications v1.9.5

Annotations

Uberon: CA1 field of hippocampus
Uberon: CA3 field of hippocampus
Uberon: cerebral cortex
Uberon: dentate gyrus granule cell layer

a(GO:"neurofibrillary tangle") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 205)) View Subject | View Object

Appears in Networks:

Tau Modifications v1.9.5

Annotations

Uberon: CA1 field of hippocampus
Uberon: CA3 field of hippocampus
Uberon: cerebral cortex
Uberon: dentate gyrus granule cell layer

p(HGNC:MAPT, pmod(Ph, Ser, 202)) positiveCorrelation p(HGNC:MAPT, var("p.Glu391*")) View Subject | View Object

Appears in Networks:

Tau Modifications v1.9.5

Annotations

Uberon: CA1 field of hippocampus
Uberon: CA3 field of hippocampus
Uberon: cerebral cortex
Uberon: dentate gyrus granule cell layer

p(HGNC:MAPT, pmod(Ph, Ser, 202)) positiveCorrelation a(GO:"neurofibrillary tangle") View Subject | View Object

Appears in Networks:

Tau Modifications v1.9.5

Annotations

Uberon: CA1 field of hippocampus
Uberon: CA3 field of hippocampus
Uberon: cerebral cortex
Uberon: dentate gyrus granule cell layer

p(HGNC:MAPT, pmod(Ph, Ser, 205)) positiveCorrelation a(GO:"neurofibrillary tangle") View Subject | View Object

Appears in Networks:

Tau Modifications v1.9.5

Annotations

Uberon: CA1 field of hippocampus
Uberon: CA3 field of hippocampus
Uberon: cerebral cortex
Uberon: dentate gyrus granule cell layer

p(HGNC:MAPT, pmod(Ph, Ser, 205)) positiveCorrelation p(HGNC:MAPT, var("p.Glu391*")) View Subject | View Object

Appears in Networks:

Tau Modifications v1.9.5

Annotations

Uberon: CA1 field of hippocampus
Uberon: CA3 field of hippocampus
Uberon: cerebral cortex
Uberon: dentate gyrus granule cell layer

p(HGNC:MAPT, var("p.Glu391*")) positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 202)) View Subject | View Object

Appears in Networks:

Tau Modifications v1.9.5

Annotations

Uberon: CA1 field of hippocampus
Uberon: CA3 field of hippocampus
Uberon: cerebral cortex
Uberon: dentate gyrus granule cell layer

p(HGNC:MAPT, var("p.Glu391*")) positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 205)) View Subject | View Object

Appears in Networks:

Tau Modifications v1.9.5

Annotations

Uberon: CA1 field of hippocampus
Uberon: CA3 field of hippocampus
Uberon: cerebral cortex
Uberon: dentate gyrus granule cell layer

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