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p(HGNC:M6PR)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
M6PR
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

The Ubiquitin–Proteasome System and the Autophagic–Lysosomal System in Alzheimer Disease v1.0.0

In-Edges 0

Out-Edges 1

p(HGNC:M6PR) increases tloc(a(MESH:Cathepsins), fromLoc(GO:"trans-Golgi network"), toLoc(GO:"multivesicular body")) View Subject | View Object

Acid hydrolases, including cathepsins, are delivered from the trans-Golgi network (TGN) to MVBs/late endosomes by either of two mannose-6- phosphate receptors: cation-dependent 46 kDa MPR (CD-MPR) and cation-independent 215 kDa MPR (CI-MPR; Mullins et al. 2001). PubMed:22908190

Appears in Networks:

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.