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bp(GO:"lysosomal lumen acidification")

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Entity

Name
lysosomal lumen acidification
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 1

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing v1.0.0

In-Edges 4

a(CHEBI:"poly(D,L-lactic acid-co-glycolic acid)") increases bp(GO:"lysosomal lumen acidification") View Subject | View Object

Third, acidic nanoparticles such as polylactic acid and poly(lactide- co-glycolide) increase acidification (BOX 3) . PubMed:30116051

Appears in Networks:

a(CHEBI:"poly(lactic acid) polymer") increases bp(GO:"lysosomal lumen acidification") View Subject | View Object

Third, acidic nanoparticles such as polylactic acid and poly(lactide- co-glycolide) increase acidification (BOX 3) . PubMed:30116051

Appears in Networks:

a(PUBCHEM:129688311) increases bp(GO:"lysosomal lumen acidification") View Subject | View Object

Second, the TFEB inducer 2-hydroxypropyl-β-cyclo- dextrin promoted the acidity of lysosomes in neurons 190 . PubMed:30116051

Appears in Networks:

act(p(HGNC:MCOLN1)) increases bp(GO:"lysosomal lumen acidification") View Subject | View Object

Fourth, activation of the lysosomal Ca 2+ channel mucol- ipin transient receptor potential channel 1 (TRPML1) with a synthetic agonist (ML-SA1) increased lysoso- mal Ca 2+ release, lowered pH and promoted Aβ clear- ance 191,192 . PubMed:30116051

Appears in Networks:

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.