HBP00056

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Entity

Name: HBP00056
Namespace: HBP
Namespace Version: None
Pattern: .*

Appears in Networks 1

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain v1.0.1

In-Edges 1

p(HBP:HBP00056) hasVariant p(HBP:HBP00056, var("p.Pro301Leu")) View Subject | View Object

Appears in Networks:

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain v1.0.1

Out-Edges 7

p(HBP:HBP00056, var("p.Pro301Leu")) increases a(HBP:HBP00006) View Subject | View Object

SEC analysis of the molecular weight distribution of tau demonstrated that rTg21221 brain extracts (PBS-soluble, 3,000g) contained primarily LMW species and very low levels of HMW tau species, whereas rTg4510 brain extract showed both HMW and LMW peaks (Fig. 2e,f). PubMed:26458742

Appears in Networks:

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain v1.0.1

Annotations

Confidence: Medium

p(HBP:HBP00056, var("p.Pro301Leu")) increases p(HBP:HBP00056, pmod(Ph, Thr, 205)) View Subject | View Object

The PBS- extractable tau species from rTg4510 brain had higher levels of phosphorylation compared with the tau species obtained from rTg21221, especially those associated with some speciﬁc phosphorylation sites such as pT205, pS262, pS400, pS404, pS409 and pS422. PubMed:26458742

Appears in Networks:

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain v1.0.1

Annotations

Confidence: Medium

p(HBP:HBP00056, var("p.Pro301Leu")) increases p(HBP:HBP00056, pmod(Ph, Ser, 262)) View Subject | View Object

The PBS- extractable tau species from rTg4510 brain had higher levels of phosphorylation compared with the tau species obtained from rTg21221, especially those associated with some speciﬁc phosphorylation sites such as pT205, pS262, pS400, pS404, pS409 and pS422. PubMed:26458742

Appears in Networks:

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain v1.0.1

Annotations

Confidence: Medium

p(HBP:HBP00056, var("p.Pro301Leu")) increases p(HBP:HBP00056, pmod(Ph, Ser, 400)) View Subject | View Object

The PBS- extractable tau species from rTg4510 brain had higher levels of phosphorylation compared with the tau species obtained from rTg21221, especially those associated with some speciﬁc phosphorylation sites such as pT205, pS262, pS400, pS404, pS409 and pS422. PubMed:26458742

Appears in Networks:

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain v1.0.1

Annotations

Confidence: Medium

p(HBP:HBP00056, var("p.Pro301Leu")) increases p(HBP:HBP00056, pmod(Ph, Ser, 404)) View Subject | View Object

The PBS- extractable tau species from rTg4510 brain had higher levels of phosphorylation compared with the tau species obtained from rTg21221, especially those associated with some speciﬁc phosphorylation sites such as pT205, pS262, pS400, pS404, pS409 and pS422. PubMed:26458742

Appears in Networks:

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain v1.0.1

Annotations

Confidence: Medium

p(HBP:HBP00056, var("p.Pro301Leu")) increases p(HBP:HBP00056, pmod(Ph, Ser, 409)) View Subject | View Object

The PBS- extractable tau species from rTg4510 brain had higher levels of phosphorylation compared with the tau species obtained from rTg21221, especially those associated with some speciﬁc phosphorylation sites such as pT205, pS262, pS400, pS404, pS409 and pS422. PubMed:26458742

Appears in Networks:

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain v1.0.1

Annotations

Confidence: Medium

p(HBP:HBP00056, var("p.Pro301Leu")) increases p(HBP:HBP00056, pmod(Ph, Ser, 422)) View Subject | View Object

The PBS- extractable tau species from rTg4510 brain had higher levels of phosphorylation compared with the tau species obtained from rTg21221, especially those associated with some speciﬁc phosphorylation sites such as pT205, pS262, pS400, pS404, pS409 and pS422. PubMed:26458742

Appears in Networks:

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain v1.0.1

Annotations

Confidence: Medium

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.