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a(CHEBI:"GW 501516")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
GW 501516
Namespace
chebi
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/chebi-names.belns

Appears in Networks 1

Nuclear receptors as therapeutic targets for Alzheimer's disease. v1.0.0

In-Edges 0

Out-Edges 6

a(CHEBI:"GW 501516") increases act(p(HGNC:PPARD)) View Subject | View Object

The PPAR-d agonist GW501516 induced expression of ABCA1 and apolipoprotein A1, a peripheral lipid transporter, in macrophages [71]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
High

a(CHEBI:"GW 501516") increases p(HGNC:ABCA1) View Subject | View Object

The PPAR-d agonist GW501516 induced expression of ABCA1 and apolipoprotein A1, a peripheral lipid transporter, in macrophages [71]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
High

a(CHEBI:"GW 501516") increases p(HGNC:APOA1) View Subject | View Object

The PPAR-d agonist GW501516 induced expression of ABCA1 and apolipoprotein A1, a peripheral lipid transporter, in macrophages [71]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
High

a(CHEBI:"GW 501516") decreases a(HBP:HBP00018) View Subject | View Object

In a study reported by Kalinin et al., treatment of 5xFAD mice with the PPAR-d agonist, GW742, resulted in decreased plaque burden and an increase in the expression of two Ab proteases, neprilysin and IDE [72]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
High

a(CHEBI:"GW 501516") increases p(HGNC:MME) View Subject | View Object

In a study reported by Kalinin et al., treatment of 5xFAD mice with the PPAR-d agonist, GW742, resulted in decreased plaque burden and an increase in the expression of two Ab proteases, neprilysin and IDE [72]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
High

a(CHEBI:"GW 501516") increases p(HGNC:IDE) View Subject | View Object

In a study reported by Kalinin et al., treatment of 5xFAD mice with the PPAR-d agonist, GW742, resulted in decreased plaque burden and an increase in the expression of two Ab proteases, neprilysin and IDE [72]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
High

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.