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  3. composite(p(HGNC:JAK2), p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))

composite(p(HGNC:JAK2), p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits"))

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Components

Appears in Networks 1

Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection. v1.0.0

In-Edges 1

bp(GO:"calcium-mediated signaling") association composite(p(HGNC:JAK2), p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")) View Subject | View Object

JAK-2, also implicated in the neuroprotective pathway, may play a role in linking nAChR action with calcium signaling, because JAK-2 phosphorylates inositol 1,4,5-triphosphate receptors through its activation of FYN (Wallace et al., 2005). PubMed:19293145

Appears in Networks:

Out-Edges 3

composite(p(HGNC:JAK2), p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")) hasComponent p(HGNC:JAK2) View Subject | View Object

Appears in Networks:

composite(p(HGNC:JAK2), p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")) hasComponent p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits") View Subject | View Object

Appears in Networks:

composite(p(HGNC:JAK2), p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")) association bp(GO:"calcium-mediated signaling") View Subject | View Object

JAK-2, also implicated in the neuroprotective pathway, may play a role in linking nAChR action with calcium signaling, because JAK-2 phosphorylates inositol 1,4,5-triphosphate receptors through its activation of FYN (Wallace et al., 2005). PubMed:19293145

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.