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complex(p(HGNC:CHRNA6), p(HGNC:CHRNB2))

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Components

Appears in Networks 1

Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system v1.0.0

This document contains the curation of the review article Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system by Taly et al. 2009

In-Edges 1

a(MESH:"Dopaminergic Neurons") association complex(p(HGNC:CHRNA6), p(HGNC:CHRNB2)) View Subject | View Object

For example, as discussed above, at least five functional nAChR subtypes have been identified in dopaminergic terminals in the striatum: α4α6β2β3, α6β2β3 and α6β2, which have the highest sensitivity to nicotine, and α4β2 and α4α5β2, which are more numerous than the α6-containing subtypes, yet with lower affinity for nicotine105,106,204. PubMed:19721446

Appears in Networks:
Annotations
MeSH
Corpus Striatum
Text Location
Review

Out-Edges 3

complex(p(HGNC:CHRNA6), p(HGNC:CHRNB2)) hasComponent p(HGNC:CHRNA6) View Subject | View Object

Appears in Networks:

complex(p(HGNC:CHRNA6), p(HGNC:CHRNB2)) hasComponent p(HGNC:CHRNB2) View Subject | View Object

Appears in Networks:

complex(p(HGNC:CHRNA6), p(HGNC:CHRNB2)) association a(MESH:"Dopaminergic Neurons") View Subject | View Object

For example, as discussed above, at least five functional nAChR subtypes have been identified in dopaminergic terminals in the striatum: α4α6β2β3, α6β2β3 and α6β2, which have the highest sensitivity to nicotine, and α4β2 and α4α5β2, which are more numerous than the α6-containing subtypes, yet with lower affinity for nicotine105,106,204. PubMed:19721446

Appears in Networks:
Annotations
MeSH
Corpus Striatum
Text Location
Review

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.