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p(HGNC:CHRNA7, pmod(Ph, Tyr))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
CHRNA7
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Chaperoning α7 neuronal nicotinic acetylcholine receptors v1.0.0

In-Edges 1

p(HGNC:CHRNA7) hasVariant p(HGNC:CHRNA7, pmod(Ph, Tyr)) View Subject | View Object

Appears in Networks:

Out-Edges 1

p(HGNC:CHRNA7, pmod(Ph, Tyr)) decreases act(p(HGNC:CHRNA7)) View Subject | View Object

Tyrosine phosphorylation of α7 AChR was found to negatively regulate receptor activity in neuroblastoma cells, hippo- campal CA1 interneurons, and supraoptic magnocellular neurons, whereas de-phosphorylation of α7 AChR was found to potentiate ACh-evoked currents in these cells. PubMed:22040696

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.