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complex(a(MESH:Ubiquitin), p(HGNC:CDC34))

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Components

Appears in Networks 1

Perilous journey: a tour of the ubiquitin–proteasome system v1.0.0

In-Edges 1

p(HGNC:CDC34) increases complex(a(MESH:Ubiquitin), p(HGNC:CDC34)) View Subject | View Object

Recent work has shown that the E2s Cdc34 (cell division cycle 34) and Ube2S (ubiquitin-conjugating enzyme E2S) also form noncovalent interfaces with ubiquitin in addition to the covalent thioester bond [23,24], suggesting that E2s catalyze ubiquitin transfer at least in part by holding ubiquitin against an interface on the E2 surface that optimizes the position of the thioester bond in the active site PubMed:24457024

Appears in Networks:

Out-Edges 2

complex(a(MESH:Ubiquitin), p(HGNC:CDC34)) hasComponent a(MESH:Ubiquitin) View Subject | View Object

Appears in Networks:

complex(a(MESH:Ubiquitin), p(HGNC:CDC34)) hasComponent p(HGNC:CDC34) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.