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complex(p(HGNC:FKBP6), p(HGNC:OSBP))

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Components

Appears in Networks 1

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways v1.0.0

In-Edges 2

a(HBP:"OSW-1") decreases complex(p(HGNC:FKBP6), p(HGNC:OSBP)) View Subject | View Object

Indeed, OSW-1 treatment led to the dissociation of OSBP from FKBP36 (Figure 3C) PubMed:25036637

Appears in Networks:

p(HGNC:FKBP6) increases complex(p(HGNC:FKBP6), p(HGNC:OSBP)) View Subject | View Object

In contrast, the highly homologous cochaperone FKBP36 (aka FKBP6) did not interact with PDCL, but instead associated with the oxysterol-binding protein OSBP (Burgett et al., 2011;Figure 3B) PubMed:25036637

Appears in Networks:

Out-Edges 2

complex(p(HGNC:FKBP6), p(HGNC:OSBP)) hasComponent p(HGNC:FKBP6) View Subject | View Object

Appears in Networks:

complex(p(HGNC:FKBP6), p(HGNC:OSBP)) hasComponent p(HGNC:OSBP) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.