1. Catalog
  2. Nodes
  3. bp(GO:"GO:0032455")

bp(GO:"GO:0032455")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
GO:0032455
Namespace
go
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/go.belns

Appears in Networks 1

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications v1.0.0

In-Edges 1

path(MESH:D000544) decreases bp(GO:"GO:0032455") View Subject | View Object

Bruno and Cuello reported that a protease cascade which converts proNGF to mature NGF (mNGF) and degrades mNGF in the extracellular space by the coordinated activity of plasminogen, tissue plasminogen activator (tPA), neuroserpin, matrix metalloproteinase (MMP)-9 and tissue inhibitor of MMP (TIMP)-1 may be defective in AD, resulting in NGF dysfunction [74]. PubMed:18986241

Appears in Networks:
Annotations
MeSH
Cognitive Dysfunction

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.