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p(HGNC:SEPT5)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
SEPT5
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

The Ubiquitin Proteasome System in Neurodegenerative Diseases: Sometimes the Chicken, Sometimes the Egg v1.0.0

In-Edges 2

complex(p(HGNC:SEPT5), p(HGNC:STX1A)) hasComponent p(HGNC:SEPT5) View Subject | View Object

Appears in Networks:

p(HGNC:PRKN, var("?")) decreases act(p(HGNC:SEPT5)) View Subject | View Object

It is possible that CDCrel-1 is involved in regulating transmitter release via its role in regulating synaptic vesicle dynamics, and its accumulation in patients with a mutation in Parkin perturbs the process. PubMed:14556719

Appears in Networks:

Out-Edges 4

p(HGNC:SEPT5) hasVariant p(HGNC:SEPT5, pmod(Ub)) View Subject | View Object

Appears in Networks:

p(HGNC:SEPT5) decreases sec(a(CHEBI:"growth hormone")) View Subject | View Object

Following transfection to a cell line, wild-type CDCrel-1 inhibits secretion of growth hormone, while the dominant-negative species increases secretion (Beites et al., 1999 PubMed:14556719

Appears in Networks:

p(HGNC:SEPT5) regulates sec(a(CHEBI:neurotransmitter)) View Subject | View Object

It is possible that CDCrel-1 is involved in regulating transmitter release via its role in regulating synaptic vesicle dynamics, and its accumulation in patients with a mutation in Parkin perturbs the process. PubMed:14556719

Appears in Networks:

p(HGNC:SEPT5) regulates act(a(GO:"synaptic vesicle")) View Subject | View Object

It is possible that CDCrel-1 is involved in regulating transmitter release via its role in regulating synaptic vesicle dynamics, and its accumulation in patients with a mutation in Parkin perturbs the process. PubMed:14556719

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.