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p(FPLX:PKA, pmod(Ph, Tyr, 330))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
PKA
Namespace
FPLX
Namespace Version
20180917
Namespace URL
https://raw.githubusercontent.com/sorgerlab/famplex/e8ae9926ff95266032cb74f77973c84939bffbeb/export/famplex.belns

Appears in Networks 1

The Spleen Tyrosine Kinase (Syk) Regulates Alzheimer Amyloid-β Production and Tau Hyperphosphorylation* v1.0.0

In-Edges 2

p(HGNC:SYK) increases p(FPLX:PKA, pmod(Ph, Tyr, 330)) View Subject | View Object

PKA is a known substrate of Syk, and it has been shown that Syk inhibits PKA activity by phosphorylating Tyr-330 of the PKA catalytic subunit (60), further supporting our observation. PubMed:25331948

Appears in Networks:

p(FPLX:PKA) hasVariant p(FPLX:PKA, pmod(Ph, Tyr, 330)) View Subject | View Object

Appears in Networks:

Out-Edges 1

p(FPLX:PKA, pmod(Ph, Tyr, 330)) decreases act(p(FPLX:PKA)) View Subject | View Object

PKA is a known substrate of Syk, and it has been shown that Syk inhibits PKA activity by phosphorylating Tyr-330 of the PKA catalytic subunit (60), further supporting our observation. PubMed:25331948

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.