Evidences a(CHEBI:"amyloid-beta") to complex(GO:"NLRP3 inflammasome complex")

NLRP3 inflammasome activation results from TLR ligation and concomitant uptake of Ab in models of AD

A few molecules, such as amyloid-β, can induce both NLRP3 priming through TLR activation and NLRP3 inflammasome activation68.

This finding was associated with spatial memory dysfunction and an increase in Abeta plaque deposition

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.