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a(HBP:acadesine)

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Entity

Name
acadesine
Namespace
HBP
Namespace Version
None
Pattern
.*

Appears in Networks 1

Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β. v1.0.0

In-Edges 0

Out-Edges 1

a(HBP:acadesine) increases act(p(ECCODE:"2.7.11.31")) View Subject | View Object

Conversely, treatment with AICAR (5-aminoimidazole-4- carboxamide ribonucleoside), an AMPK activator (34), increased the inhibitory phosphorylation of GSK3b and reduced tau phosphorylation at Ser396/404 in SH-SY5Y cells and cortical neurons PubMed:22419736

Appears in Networks:

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.