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complex(p(HGNC:PSMC4), p(HGNC:SNCA))

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Components

Appears in Networks 1

The Ubiquitin Proteasome System in Neurodegenerative Diseases: Sometimes the Chicken, Sometimes the Egg v1.0.0

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Out-Edges 3

complex(p(HGNC:PSMC4), p(HGNC:SNCA)) hasComponent p(HGNC:PSMC4) View Subject | View Object

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complex(p(HGNC:PSMC4), p(HGNC:SNCA)) hasComponent p(HGNC:SNCA) View Subject | View Object

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complex(p(HGNC:PSMC4), p(HGNC:SNCA)) decreases act(complex(GO:"proteasome complex")) View Subject | View Object

An important finding, however, in that respect is that aggregated and even monomeric alphaSYN bind to the S6' proteasome subunit and inhibit proteasomal function (Snyder et al., 2003). PubMed:14556719

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.